The Testosterone Cascade: How Your Body Actually Makes Testosterone (And Where It Goes Wrong)
Testosterone isn’t just a “male hormone” - it’s vital for energy, mood, muscle, fat distribution, and brain function. This guide explains how your body...
The Signal
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Not marketing claims. Published research.
Every ingredient in Pregen has been studied in peer-reviewed, randomized, controlled human trials. We've published the research. You can read it yourself.
57%
Increase in testosterone with KSM-66 Ashwagandha vs. placebo (Wankhede et al., 2015)
40%
Reduction in cortisol with KSM-66 at 600mg/day (Chandrasekhar et al., 2012)
17×
Increase in NAD+ cellular energy with NMN supplementation (Yi et al., 2023)
FAQ's
Get quick answers to some of the most asked questions by customers
Is Pregen a testosterone replacement therapy (TRT)?
No. Pregen does not add testosterone to your body — it supplies the raw materials your body uses to produce its own naturally. This is a supplement, not hormone therapy.
How long before I notice results?
Most customers report initial improvements in energy and sleep within 2–3 weeks. Measurable changes in body composition and libido typically emerge at 6–8 weeks of consistent daily use.
Can I take Pregen with other medications?
Consult your doctor before combining with any prescription medication, particularly statins, blood thinners, or hormone-related medications.
Why is pregnenolone included if DHEA is already in the formula?
Pregnenolone sits above DHEA in the hormone cascade. By supplying both, we support the complete pathway — not just one step. It's also the ingredient the brand is named after.
What makes Pregen different from other testosterone supplements?
Most testosterone boosters focus on late-stage support (zinc, fenugreek, Tongkat Ali). Pregen starts upstream — at pregnenolone, the very beginning of the process. We also include NMN for cellular energy and a high-potency Omega-3 softgel, making it a genuinely comprehensive daily system.
Is Pregen safe for long-term use?
All ingredients have established safety profiles at the doses used. The methylated B vitamins, D3/K2, zinc, magnesium, and Omega-3 are nutrients widely recommended for long-term supplementation. Pregnenolone and DHEA are generally well-tolerated; we recommend consulting your doctor for long-term use, especially for men with hormone-sensitive conditions.
Is this subscription locked in?
No. You can cancel, pause, or modify your subscription at any time in your account. No hidden fees, no cancellation penalties.